Clinical trials

# Trials that could offer more options

Our clinical trials evaluate a targeted, oral therapy for people living with difficult-to-treat cancers. If a study could be right for you, we'll help you understand every step.

Ask about eligibility → Patient FAQ

Current studies

## Open and enrolling programs

Phase 3 · ASPENOVA Enrolling

### Cyclin E1-positive platinum-resistant ovarian cancer

A global, registration-intent trial evaluating oral Zent-001 in biomarker-defined patients who have progressed on platinum-based therapy.

- Design Randomized, global
- Key criterion Cyclin E1 positive
- Dosing Oral, once daily
- Sites 40+ worldwide

Check eligibility →
Phase 2 · Registration-intent Advancing

### Uterine serous carcinoma

A biomarker-defined study evaluating Zent-001 in uterine serous carcinoma — a population with a significant, ongoing unmet need.

- Design Registration-intent
- Key criterion Biomarker-defined
- Dosing Oral, once daily
- Sites US & EU

Check eligibility →
Find a site 40+ trial sites across the US and EU Our team can help locate the nearest participating center.

Before you decide

## What to expect as a participant

Deciding whether to join a trial is personal. Here's what participation typically involves — and what we do to support you.

- An informed consent discussion — ask anything, take your time
- Biomarker screening at a participating site
- Regular study visits and close monitoring by your care team
- Travel and scheduling support where available
- You can leave a trial at any time, for any reason

Talk to our patient team → Read the FAQ
"

> Participation is always voluntary. We're here to make sure you understand the science, the schedule and the support — so you can decide with confidence.

— Zentia Patient Information Team
Find a site near you → About the therapy